Results 211 to 220 of about 34,776,577 (248)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

CrossFit participants' experiences of balancing family, work, and fitness in a South African context. [PDF]

Front Psychol
O'Brien C, Koen V.
europepmc   +1 more source

Grief in Neurosurgery: Reframing Loss and Identity Through Lived Experience. [PDF]

Neurosurg Pract
Walker EN, Raturi V, Botterbush KS, Kimata AR, Pugazenthi S, Bauman MMJ, Parney I, Kicielinski K, Muraszko K, Recinos V, Timmons S, Snyder L, Pannullo SC, Juthani R, Richardson AM, Rahman M.   +15 more
europepmc   +1 more source

From 'My world fell apart' to 'The best thing that happened in my life': elite athletes' longitudinal journeys after an injury. [PDF]

BMJ Open Sport Exerc Med
Bolling C, Weiler R, T Finnoff J, Mmj Kerkhoffs G, L Tol J, Crossley KM, Della Villa F, Gouttebarge V, Verhagen E.   +8 more
europepmc   +1 more source

Leaky Bodies and Everyday Disclosure and Exposure in the Neurodegenerative Illness Stories of Younger People With Parkinson's Disease. [PDF]

Sociol Health Illn
Johnstone L, Davis M, Warren N.
europepmc   +1 more source

The hidden curriculum of endurance: how students' psychosocial stress becomes normalised in arts higher education. [PDF]

Int J Qual Stud Health Well-being
Procházková B, Zábrodská K.
europepmc   +1 more source