Results 91 to 100 of about 611,301 (351)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

NEUROPSYCHIC AND SOCIAL ASPECTS OF READINESS FOR THE SCHOOL EDUCATION OF PREPARATORY GROUP CHILDREN IN PRESCHOOL EDUCATIONAL INSTITUTIONS

open access: yesМать и дитя в Кузбассе, 2022
The aim of the investigation is to study neuropsychic and social aspects of children’s school maturity. The research considers 7 year-old children in preparatory groups of preschool educational institutions in Kemerovo. Materials and methods.
Илья Александрович Селиверстов   +4 more
doaj  

Perbedaan Kemampuan Bersosialisasi dan Kematangan Emosional Anak PAUD dan Non PAUD

open access: yesJurnal Berita Ilmu Keperawatan, 2018
Social development is a process of learning to adjust to the morals, traditions, norms and communicate with each other and work together to reach maturity in social relations.
Dian Afriyanto, Siti Arifah
doaj   +1 more source

A model to assess customer alignment through customer experience concepts

open access: yes, 2019
Business and Information Technology Alignment (BITA) has been one of the main concerns of IT and Business executives and directors due to its importance to overall company performance, especially today in the age of digital transformation.
F Buttle   +9 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The influence of executive function therapy on improving social maturity in children with Attention Deficit Hyperactivity Disorder (ADHD): An experimental study

open access: yesPsikohumaniora: Jurnal Penelitian Psikologi
Children with Attention Deficit Hyperactivity Disorder (ADHD) have non-adaptive behavioral problems related to social maturity, which impact their future lives as adults, thus necessitating access to appropriate treatment. This experimental study aims to
Taufik Hidayat   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Maturity of risk management in agricultural supply chains [PDF]

open access: yesRAUSP Management Journal
Purpose – This paper aims to assess the maturity level in the strategic risk management of an agricultural cooperative’s supply chain. Design/methodology/approach – A descriptive qualitative research approach was employed for a case study. Four interview
Ezequiel Scopel   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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