Results 111 to 120 of about 611,301 (351)
Social transfers and chronic poverty: objectives, design, reach and impact [PDF]
In the first decade of the new century, social transfer programmes emerged as a new paradigm in the fight against poverty in the global South. These programmes currently reach more than 860 million people worldwide.
Barrientos, Armando +1 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Harnessing technology review 2008. The role of technology and its impact on education. Full report. [PDF]
, 2008 This is the second review of the use and impact of ICT in the education system following the publication of the Government's e-Strategy for education, known as Harnessing Technology.
Davies, Steve, Pittard, Vanessa
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
HUBUNGAN ANTARA KEMATANGAN EMOSI DAN PENYESUAIAN SOSIAL DENGAN ALIENASI PADA SISWI SMP ISLAM TERPADU IHSANUL FIKRI BOARDING SCHOOL MAGELANG [PDF]
, 2013 Alienation is a condition when people feel estrange and insignificant in the social environment. The high emotional maturity and social adjustment will help to reduce the alienation level among the schoolgirls of boarding school who are
Ningrum, Winda Kartika
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Ekonomi, Politika & Finans Araştırmaları DergisiThis study explores the impact of digital maturity on the environmental, social, and governance (ESG) performance of Turkish companies listed on Borsa Istanbul.
Mine Aksoy +5 more
doaj +1 more source