Results 91 to 100 of about 15,136,900 (402)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A review of empirical research on pedagogical content knowledge in EFL and ESL contexts (2015–2024)
Cogent EducationThis study reviews the literature on Pedagogical Content Knowledge (PCK) research with a focus on English as a Foreign Language (EFL) and English as a Second Language (ESL) teaching.
Yuan Jiang +3 more
doaj +1 more source
Why Americans Use Social Media [PDF]
, 2011 Presents survey findings about motivations for social media use such as staying in touch with family and friends, contacting old friends, and connecting with others who share hobbies or interests, by age, gender, parental status, and other ...
Aaron Smith
core
The future of social media in marketing
Journal of the Academy of Marketing Science, 2019 Social media allows people to freely interact with others and offers multiple ways for marketers to reach and engage with consumers. Considering the numerous ways social media affects individuals and businesses alike, in this article, the authors focus ...
G. Appel +3 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
La Formación Archivística en San Luís Potosí. Reflejo de una necesidad nacional
Documentación de las Ciencias de la Información, 2012 Este trabajo presenta, de manera general, el desarrollo de la archivística hasta alcanzar su estamento de ciencia y, por otra parte, la influencia del quehacer organizativo de los documentos existentes y su tratamiento como una ciencia y la formación de ...
Guadalupe Patricia Ramos Fandiño +1 more
doaj
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Teens, Social Media, and Privacy [PDF]
, 2013 Teens share a wide range of information about themselves on social media sites; indeed the sites themselves are designed to encourage the sharing of information and the expansion of networks.
Aaron Smith +6 more
core
Human Vaccines & Immunotherapeutics, 2020 Despite major advances in vaccination over the past century, resurgence of vaccine-preventable illnesses has led the World Health Organization to identify vaccine hesitancy as a major threat to global health.
N. Puri +3 more
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source