Results 151 to 160 of about 15,136,900 (402)

“School Strike 4 Climate”: Social Media and the International Youth Protest on Climate Change

, 2020
Shelley Boulianne, Mireille Lalancette, David Ilkiw   +2 more
openalex   +2 more sources

Assessing the need for a pre‐exposure prophylaxis programme using the social media app Grindr® [PDF]

, 2017
Benjamin Hampel, Katharina Kusejko, Dominique L. Braun, Jack Harrison-Quintana, Roger D. Kouyos, Jan Fehr   +5 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Teens, Tech, and Talk: Adolescents’ Use of and Emotional Reactions to Snapchat’s My AI Chatbot

Behavioral Sciences
Due to technological advancements such as generative artificial intelligence (AI) and large language models, chatbots enable increasingly human-like, real-time conversations through text (e.g., OpenAI’s ChatGPT) and voice (e.g., Amazon’s Alexa).
Gaëlle Vanhoffelen, Laura Vandenbosch, Lara Schreurs   +2 more
doaj   +1 more source

Anti-social media [PDF]

To inform the discussion over free speech and hate speech, this study examines the way racial, religious and ethnic slurs are employed on Twitter. Executive summary: How to define the limits of free speech is a central debate in most modern democracies.
Jamie Bartlett, Jeremy Reffin, Noelle Rumball, Sarah Williamson   +3 more
core  

Empowering protest through social media [PDF]

, 2011
Advances in personal communications devices including smartphones, are enabling individuals to establish and form virtual communities in cyberspace. Such platforms now allow users to be in continuous contact, enabling them to receive information in real ...
O\u27Rourke, Simon
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Supporting Early Childhood Preservice Teachers to Effectively Integrate STEM in Their Future Teaching Practice

Education Sciences
It is critical that teachers are equipped with Science, Technology, Engineering and Mathematics (STEM) skills and knowledge as we move into a digital future.
Sarika Kewalramani, Anamika Devi, Andrea Ng   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Openness to the Metaverse Workplace: Zoom Fatigue and Metaverse Information Seeking Mediate Gender Inequities

Human Behavior and Emerging Technologies
The metaverse—a network of three-dimensional virtual worlds in which people can engage in everyday activities—could augment future workplaces given the widespread acceptance of remote work.
Chaeyun Lim, Rabindra Ratan, Swati Pandita, Maxwell Foxman, Gabriel E. Hales, Hanjie Liu, Yiming Skylar Lei, David Beyea   +7 more
doaj   +1 more source