Results 31 to 40 of about 672,505 (264)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Effects of antivaccine tweets on COVID-19 vaccinations, cases, and deaths

EPJ Data Science
Despite the wide availability of COVID-19 vaccines in the United States and their effectiveness in reducing hospitalizations and mortality during the pandemic, a majority of Americans chose not to be vaccinated during 2021. Recent work shows that vaccine
John Bollenbacher, Filippo Menczer, John Bryden   +2 more
doaj   +1 more source

Let the Weakest Link Go! Empirical Explorations on the Relative Importance of Weak and Strong Ties on Social Networking Sites

Societies, 2014
Theoretical approaches as well as empirical results in the area of social capital accumulation on social networking sites suggest that weak ties/bridging versus strong ties/bonding social capital should be distinguished and that while bonding social ...
Nicole C. Krämer, Leonie Rösner, Sabrina C. Eimler, Stephan Winter, German Neubaum   +4 more
doaj   +1 more source

Social Media and Social Entrepreneurship [PDF]

, 2019
Information plays an important role in the individual lives of people, and social media as an aspect of online information phenomenon is an exciting topic to explore in terms of its impact on social entrepreneurship. Many theoretical fields have contributed to the development of social entrepreneurship, looking in particular at the financial, political,
Islam, Md Nazmul, Chitran, Vivek
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Account credibility inference based on news-sharing networks

EPJ Data Science
The spread of misinformation poses a threat to the social media ecosystem. Effective countermeasures to mitigate this threat require that social media platforms be able to accurately detect low-credibility accounts even before the content they share can ...
Bao Tran Truong, Oliver Melbourne Allen, Filippo Menczer   +2 more
doaj   +1 more source

A Two-Study Approach to Explore the Effect of User Characteristics on Users’ Perception and Evaluation of a Virtual Assistant’s Appearance

Multimodal Technologies and Interaction, 2018
This research investigates the effect of different user characteristics on the perception and evaluation of an agent’s appearance variables. Therefore, two different experiments have been conducted. In a 3 × 3 × 5 within-subjects design
Carolin Straßmann, Nicole C. Krämer
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source