Results 141 to 150 of about 27,898,979 (247)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The relationship between physical exercise and social media addiction among Chinese university students: a random intercept cross-lagged panel model analysis

BMC Psychology
Background In the digital era, Social Media Addiction has emerged as a prominent issue affecting the mental health of university students. Despite evidence linking physical exercise to lower Social Media Addiction, it remains unknown whether within ...
Yuantai Fu, Jiaqi Wang, Renchun Liang, Caixia Li, Jian Sun   +4 more
doaj   +1 more source

The relationship between social media addiction levels and happiness levels among healthcare professionals

Frontiers in Psychology
Background and aimsThis study was conducted cross-sectionally using a descriptive-correlational approach. Study aimed to examine the relationship between healthcare professionals ‘social media addiction and their level of happiness.MethodsThe data was ...
Gulseren Citak Tunc, Büşra Köse
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Relationship Between Social Media Addiction and Self-Esteem in Medical Students of Diponegoro University

Jurnal Kedokteran Diponegoro
Background: In the modern era, social media has become a necessity in carrying out daily activities. Playing social media too often can have negative effects. These negative effects include addiction.
Difa Maulana Subiyakto, Fanti Saktini, Tanjung Ayu Sumekar   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Social Media Behaviors and Psychosocial Predictors of Social Media Addiction

, 2018
Social media addiction is an ongoing problem. Maladaptive social and personal factors associated with addiction can include: • Preoccupation with social media; • Withdrawal symptoms; • Replacing important activities (sleep, eating) with social media use;
Dailey, Stephanie, Ceballos, Natalie A., Grimes, Tom, Howard, Krista, Roming, Sinjin M.P.   +4 more
core   +1 more source

Low self esteem contributes to medical student social media addiction through chain mediation by academic Involution and anxiety

Scientific Reports
This study aimed to investigate the impact of low self-esteem on social media addiction among medical students, as well as the underlying mechanisms involving academic involution and anxiety.
Xiaodi Ma, Bing Li, Hong Nie, Wenlong Ding, Ruirui He, Wanyu He, Wanting Liu   +6 more
doaj   +1 more source