Results 51 to 60 of about 758,685 (297)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Social Media Strategic Plan For Under Armour [PDF]
, 2014 This thesis is a study of the effects of social media on an organization’s integrated marketing communications strategy in general and provides a proposal of how the sports apparel company Under Armour could use social media to enhance its promotional ...
Leers, Ashley
core +2 more sources
A Network Topology Approach to Bot Classification
, 2018 Automated social agents, or bots, are increasingly becoming a problem on social media platforms. There is a growing body of literature and multiple tools to aid in the detection of such agents on online social networking platforms.
Aiello Luca Maria +5 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Leveraging Social Media to Promote EvidenceBased Continuing Medical Education [PDF]
, 2017 Importance New dissemination methods are needed to engage physicians in evidence-based continuing medical education (CME). Objective To examine the effectiveness of social media in engaging physicians in non-industry-sponsored CME.
Flynn, Simone +5 more
core +4 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
What Strategies do Companies use to Transform Employees into Social Media Advocates? [PDF]
, 2015 There is an overwhelming consensus among researchers that employees have the potential to become excellent social ambassadors for their company. Readers of social media sites believe employees to be credible representatives of their organization, and ...
Drori, Elad
core +1 more source
Government and Social Media: A Case Study of 31 Informational World Cities
, 2014 Social media platforms are increasingly being used by governments to foster user interaction. Particularly in cities with enhanced ICT infrastructures (i.e., Informational World Cities) and high internet penetration rates, social media platforms are ...
Hartmann, Sarah +3 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Knowledge and Use of Social Media for Marketing among Poultry Farmers in Enugu State
Torkwase Journal of Agricultural ResearchObjective: This study examines the knowledge and use of social media for marketing among poultry farmers in Enugu State. Methodology: This study employed a descriptive survey design and examined 385 poultry farmers in Enugu State.
Victoria Nmesoma Ogumba
doaj +1 more source