Results 71 to 80 of about 758,685 (297)

Social Media and Platform Historiography: Challenges and Opportunities

TMG Journal for Media History, 2019
In this article, we propose a methodological outlook for historical platform studies to increase the prominence of platform historiography in the field and practice of web history and archiving. We discuss the challenges of social media archiving and the research opportunities for ‘platform’ historiography by focusing on the distinctive characteristics
Helmond, A., van der Vlist, F.N.
openaire   +6 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

WeChat Social Media Platform

SOCIAL REVIEW. International Social Sciences Review / Revista Internacional de Ciencias Sociales
En un mundo interconectado, China destaca por su ecosistema digital único, moldeado por el Proyecto Escudo Dorado, que bloquea muchas plataformas globales. WeChat, la superapp líder en China con más de 1.300 millones de usuarios activos mensuales, es esencial en la vida diaria digital.
Marzia Brandolese, Lorenza Scaldaferri
openaire   +1 more source

Qualitative Research on Youths’ Social Media Use: A review of the literature [PDF]

, 2018
In this article we explore how educational researchers report empirical qualitative research about young people’s social media use. We frame the overall study with an understanding that social media sites contribute to the production of neoliberal ...
Hughes, Hilary E, Kutner, Mel, Schmeichel, Mardi   +2 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Strategies and effectiveness analysis of modern marketing methods: A comparative study based on influencer marketing and traditional advertising marketing [PDF]

SHS Web of Conferences
This study examines the evolution of advertising from traditional media to social media platforms and analyzes how consumer engagement on different social media platforms impacts advertising effectiveness.
Liu Hongjie
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Social Media Entrepreneurship, an Agent for Sustainable Development in Developing Countries: Case Study of South Africa

International Journal of Applied Research in Business and Management
As a result of the ever-improving network accessibility, the past two decades have witnessed a rapid increase in the number of social media platforms and subscribers to these networks.
Solomon Madzvamuse, Carol Maravanyika
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Patterns and Factors of Political Disconnection on Social Media: A Cross-Platform Comparison

Media and Communication
There is a growing body of literature on the use and selection of social media platforms for political activism. However, less attention has been given to identifying citizens who are politically disconnected—those registered on social media platforms ...
Felix-Christopher von Nostitz, Marie Neihouser, Giulia Sandri, Tristan Haute   +3 more
doaj   +1 more source