Results 91 to 100 of about 758,685 (297)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Social Media Usage: A Comparison of Public Relations/Journalism and Marketing/Management Students [PDF]

open access: yes, 2013
Research indicates that students use social media for more social reasons than professional reasons. To test the assumptions in the literature, this study examined key disciplines having a professional connection to undergraduate studies.
Baker, Jabril   +2 more
core   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

“Left on read” examining social media users’ lurking behavior: an integration of anxiety and social media fatigue

open access: yesFrontiers in Psychology
IntroductionWith the widespread use of social media, the behavior and mindset of users have been transformed, leading to a gradual increase in lurking users, which can impede the sustainable development of social media platforms. In this study, we aim to
Xiaoyu Liu   +5 more
doaj   +1 more source

‘Good uni: quality nightlife’. How harvesting tweets opens up a new world of valuable qualitative data [PDF]

open access: yes, 2012
The qualitative data that is freely available on social media platforms has huge potential. Drawing on his research into what Twitter can tell us about the popularity of universities, Geraint Johnes writes that Twitter and Facebook messages could be the ...
Johnes, Geraint
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Philanthropy and Social Media [PDF]

open access: yes, 2011
We define social media as online or digital technologies that serve to connect people, information and organisations through networks. The term evolved as a way to -distinguish the emerging online -information platforms from traditional "broadcast media"
Aphra Sklair, Daisy Wakefield
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Social Media Platforms

open access: yesGeographic Information Science & Technology Body of Knowledge, 2020
Xi Gong, Xining Yang
openaire   +2 more sources

Social Media Journeys – Mapping Platform Migration

open access: yesProceedings of the Extended Abstracts of the CHI Conference on Human Factors in Computing Systems
As people engage with the social media landscape, popular platforms rise and fall. As current research uncovers the experiences people have on various platforms, rarely do we engage with the sociotechnical migration processes when joining and leaving them.
Artur Solomonik, Hendrik Heuer
openaire   +2 more sources

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