Results 101 to 110 of about 881,130 (297)
Digital Media Dependency, Relational Orientation and Socaial Networking among College Students [PDF]
, 2014 This study focused on digital media dependency, relational orientation, and demographic variables as potential factors that were relevant to the usage of social networking websites (e.g., MySpace and Facebook) among college students.
Bahk, C. Mo +3 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Social Media Usage: A Comparison of Public Relations/Journalism and Marketing/Management Students [PDF]
, 2013 Research indicates that students use social media for more social reasons than professional reasons. To test the assumptions in the literature, this study examined key disciplines having a professional connection to undergraduate studies.
Baker, Jabril +2 more
core +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Analysis of Social Media Usage on Marketing Division in Promoting Travello Hotel Bandung. Rizka Deviasani 127010029 [PDF]
, 2016 The research is entitled “Analysis of Social Media Usage on Marketing Division in Promoting Travello Hotel Bandung”. It attempts to analyze the social media usage to promoting Travello Hotel Bandung.
RIZKA DEVIASANI DAN FEGGY LESTARI DAN HERMAN HOVMAN
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Use of Social Media in Presidential Campaigns: Do Social Media Have an Effect on the Political Behavior of Voters Aged 18-24? [PDF]
, 2011 Today, the idea of social media is radically different from the media of a decade ago. While a decade ago the Internet was considered new media, our society now turns to Facebook, Twitter, and blogs as sources of information.
Hamilton, Samantha
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source