Results 121 to 130 of about 730,214 (312)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Use of Social Media in the Practice of Medicine [PDF]

open access: yesThe American Journal of Medicine, 2022
Nathan T. Connell   +2 more
openaire   +2 more sources

Use of Social Media across Different Generations in Higher Education in a Developing Country

open access: yes, 2014
While social media is increasing its extent and reach every day, research shows that its impact seems to be more intense in developing countries for various reasons.
Schoreels, Cyril   +3 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Case Study: The Ethics of Native Advertising on Social Media

open access: yes, 2019
This case study is part of a series on the ethics of social media data use by third ...
Ryerson University Social Media Lab
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Use of Social Media for Agricultural Business among Farmers in Enugu State

open access: yesTorkwase Journal of Agricultural Research
Objective: This study examined the use of social media platforms for agricultural business among farmers in Nigeria.  Methodology: The researcher used a descriptive survey design in the study.
Elizabeth Chiamaka Ogbuefi
doaj   +1 more source

Case Study: The Ethics of Live streams on Social Media

open access: yes, 2019
This case study is part of a series on the ethics of social media data use by third ...
Ryerson University Social Media Lab
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Social Media Use Among University Students

open access: yesPakistan Journal of Information Management & Libraries
The use of social media has become widespread in recent years. It is an excellent source of social interaction, and students routinely use various social media platforms for different academic activities.
Muhammad Arif   +3 more
doaj  

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