Results 131 to 140 of about 3,546,196 (306)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

The Relationships Between Social Support Seeking, Social Media Use, and Psychological Resilience Among College Students

Psychology Research and Behavior Management
Rong Wang,1 Zeqing Mao,2 Xiao Gu3 1College of Art and Design, Xihua University, Chengdu, Sichuan, People’s Republic of China; 2School of Cultural Creativity and Management, Communication University of Zhejiang, Hangzhou, Zhejiang, People’s Republic of ...
Wang R, Mao Z, Gu X
doaj  

Look who's talking [PDF]

, 2007
Major museums worldwide are starting to use social media such as blogs, podcasts and online video to encourage users to participate in their programs.
Chan, Sebastian, Russo, Angelina, Watkins, Jerry J.   +2 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Media fragment indexing using social media

, 2014
With more and more video resources shared on the Web, the practice of sharing a video object from a certain time point (deep-linking) has been implemented by many video sharing platforms. With so many media fragments created, annotated and shared, however, indexing video objects on a fine-grained level on the Web scale is still not implemented by major
Li, Yunjia, Troncy, Raphael, Wald, Mike, Wills, Gary   +3 more
openaire   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Meerdere schermen in de huiskamer: een onderzoek naar simultaan mediagebruik [PDF]

, 2012
Today’s (home) media environment is becoming increasingly saturated. Smartphones, tablets and laptops enter our living rooms and possibly alter our television viewing experience.
Courtois, Cédric, D'heer, Evelien, Paulussen, Steve   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Institutional health communication and social media: Exploring Italian hospitals’ use of social media pages

Digital Health
Introduction Hospitals play a potentially crucial role in public health, and social media can be powerful tools to reach their target audiences but are hospitals exploiting them to their full potential? Methods We retrieved the institutional webpages and
Carlotta Fiammenghi, Loredana Covolo, Anna Vanoncini, Umberto Gelatti, Elisabetta Ceretti   +4 more
doaj   +1 more source