Results 51 to 60 of about 730,214 (312)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Is Social Media Use Disorder a Thing?

Psychiatry International
Background: As understanding of addiction extends beyond substance misuse, various behavioral disorders may emerge as recognized mental health conditions, including social media use disorder (SMUD). To date, however, empirical research supporting SMUD as
David Desatnik, Moshe Shmueli, Nofar Tsur, Ariel Pollock Star, Norm O’Rourke   +4 more
doaj   +1 more source

Transitions in social media use and social media use for transition

Proceedings of the International Conference on Networked Learning
High school and college students are known to be heavy users of social media. Much of their use is focused on peer social interactions and entertainment, but social media is also a potential platform for informal networked learning. In this study, we examine how college students used social media to learn about and prepare for college, how they use it ...
Vanessa P. Dennen, Lauren M. Bagdy
openaire   +1 more source

Journalists views and use of social media: Cision Social Journalism Study 2012: global report [PDF]

, 2012
The annual Social Journalism Study conducted by Cision and Canterbury Christ Church University, UK, is charting the changes of how journalists and media professionals use social media for work.
Rehkopf, F., Canterbury Christ Church University, Cision Germany, Gulyas, A., Pole, K.   +4 more
core  

Adolescent social media use and well-being [PDF]

, 2020
Section A: Presents a thematic synthesis and appraisal of literature, using a systematic search methodology of qualitative research on the views and experiences of adolescents of social media and well-being.
Shankleman, M.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Peer-reported social adjustment and social media use patterns among adolescents: A latent profile analysis

Computers in Human Behavior Reports
This study examined the association between adolescents' peer-reported social adjustment and their social media use (SMU) patterns. Participants were 716 Dutch adolescents (Mage = 13.2 years, 48.3 % girls).
Sanyogita S. Khare, J. Loes Pouwels, Hanneke Hendriks, Roy Otten   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Motivations for Traditional Social Media Use: The Case of Facebook Users [PDF]

, 2023
The purpose of this study is to examine the general profile of traditional social media users and to identify the activities of users in the social media environment.
Josip Herceg, Matea Matic Sosic
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source