Results 71 to 80 of about 730,214 (312)

Social media and professional networking: a case of information professionals in the SCECSAL region [PDF]

open access: yes, 2012
The purpose of the study was to establish the extent to which library and information professionals in the Standing Conference of Eastern, Central and Southern Africa Library and Information Associations (SCECSAL) region are using social media ...
Chisenga, Justin, Chande-Mallya, Rehema
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The Use of Social Media by UK Local Resilience Forums

open access: yes, 2014
The potential uses of social media in the field of emergency preparedness, resilience and response (EPRR) are varied and interesting. The UK government have produced guidance documents for its use in the UK EPRR field but evidence of use is poorly ...
Meaton, Julia, Stringer, Lisa
core  

Mindfulness and the social media

open access: yes, 2014
The number of people engaging in and using social media has increased substantially over the past decade. Recent research has also suggested that a minority of individuals appear to be addicted to social media (e.g., so-called ‘Facebook addiction ...
Van Gordon, W, Shonin, E, Griffiths, MD
core   +1 more source

Urban & Online: Social Media Use among Adolescents and Sense of Belonging to a Super-Diverse City [PDF]

open access: yes, 2019
In a world of continuous migration, super-diverse cities consist of a multitude of migrants and non-migrants from a variety of cultural backgrounds. Yet one characteristic they all have in common is the place where they currently live.
Eldik, A.K. (Anne) van   +9 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Investigating the Dynamics of Social Media Addiction and Well-Being in Jordan: An Empirical Analysis

open access: yesSocial Sciences
This study examines the complex associations among social media usage, engagement, addiction and subjective well-being. Employing a sophisticated framework that integrates both first- and second-order models, this study employs structural equation ...
Islam Habis Mohammad Hatamleh   +1 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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