Results 171 to 180 of about 3,477,145 (304)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Incorporation of social medicine curriculum in academic and community health centres: a scoping review protocol. [PDF]
Cydis M +4 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The Future of Healthcare Management: A Social Medicine Perspective. [PDF]
Tocco Tussardi I.
europepmc +1 more source
Healing Through History: a qualitative evaluation of a social medicine consultation curriculum for internal medicine residents. [PDF]
Bradley J +5 more
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Navigating Ottawa Resources To improve Health: a virtual student-clinic pilot to strengthen social medicine education. [PDF]
Lee SH +7 more
europepmc +1 more source

