Results 151 to 160 of about 1,502,953 (305)

The design and implementation of a longitudinal social medicine curriculum at the University of Vermont's Larner College of Medicine. [PDF]

BMC Med Educ, 2021
Goyal RK, Dawson CA, Epstein SB, Brach RJ, Finnie SM, Lounsbury KM, Lahey T, Eldakar-Hein ST.   +7 more
europepmc   +1 more source

La Medicina Social y el genocidio

  We social medicine practitioners thus joined the worldwide call to halt to the genocide. We spoke on behalf of the people’s health, in concert with protesters, including many Jewish activists, worldwide; the U.N.
Board , Editorial, Editorial Board
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Current Issues in Social Medicine and Public Health from the Viewpoint of Early-career Researchers: Summary of Opinions at the Social Medicine Young Retreat.

JMA J, 2022
Harada KH, Hara K, Yamamoto T, Endo M, Uchida M, Kuwahara K.   +5 more
europepmc   +1 more source

Problems in Social Medicine Related to Alcohol and Deaths: Autopsy Cases in the Southern Part of Osaka City. [PDF]

Subst Abuse Rehabil, 2021
Tani N, Ikeda T, Hirokawa T, Aoki Y, Shida A, Ikeda K, Morioka F, Ishikawa T.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Correction to: The design and implementation of a longitudinal social medicine curriculum at the University of Vermont's Larner College of Medicine. [PDF]

BMC Med Educ, 2021
Goyal RK, Dawson CA, Epstein SB, Brach RJ, Finnie SM, Lounsbury KM, Lahey T, Eldakar-Hein ST.   +7 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Characteristics of individuals registered in the national registries in social medicine departments in Denmark 2012-2022: a descriptive cohort study. [PDF]

BMJ Public Health
Button MSF, Kårhus LL, Frost P, Renneberg J, Petersen J.   +4 more
europepmc   +1 more source