Results 131 to 140 of about 15,576,902 (304)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

O problema do conhecimento verdadeiro na epidemiologia

open access: yesRevista de Saúde Pública
São examinadas as bases filosóficas da validação do conhecimento científico, com o intuito de estabelecer uma visão crítica a respeito da adoção das proposições de Popper na epidemiologia.
José Ricardo de Carvalho Mesquita Ayres
doaj  

Determination of the Need and Assessment Algorithms of the Scope of Activity of Regional Centers for Diagnosis and Treatment of Bronchopulmonary Dysplasia

open access: yesGalician Medical Journal, 2016
Graphical and polynomial (quantitative) regional model of bronchopulmonary dysplasia (BPD) prevalence, depending on the number of premature children, was substantiated, composed and proposed for use for the first time.
A. F. Shypko
doaj  

Boston University School of Medicine catalog [PDF]

open access: yes, 1876
Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Boston University School of Medicine catalog [PDF]

open access: yes, 1890
Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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