Results 121 to 130 of about 15,576,902 (304)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Between Bureaucracy and Community

open access: yesSvetovi
This article explores how collaboration operates as both a concept and a practice in the post-socialist public health systems of Serbia and Croatia. Drawing on ethnographic research and expert interviews, it identifies diverse, often conflicting forms ...
Jelena Kupsjak, Ljiljana Pantović
doaj   +1 more source

Boston University School of Medicine catalog [PDF]

open access: yes, 1902
Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Pensamento clássico da saúde pública paulista na era dos centros de saúde e educação sanitária

open access: yesRevista de Saúde Pública
Revisão histórica sobre ideias e conceitos da organização sanitária que se seguiram à introdução do modelo do Centro de Saúde distrital pela reforma do Serviço Sanitário em 1925.
Guilherme Arantes Mello
doaj  

Green economy and green technologies in Russia: opportunities and prospects: social medicine in the regions that have experienced poor socio-political situation and ways to resolve some of these difficulties

open access: yesRUDN Journal of Ecology and Life Safety, 2014
In the paper the problems of greening the economy of Russia, problems of transition to sustainable development, the green economy, which was designed to improve people’s well-being and social justice and to considerably reduce the risks to the ...
S A Lipina
doaj  

Boston University School of Medicine catalog [PDF]

open access: yes, 1906
Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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