Overcoming Expert Disagreement In A Delphi Process. An Exercise In Reverse Epistemology [PDF]
Disagreement among experts is a central topic in social epistemology. What should an expert do when confronted with the different opinion of an epistemic peer?
Elisabetta, Lalumera
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Practical Application Primer on Cognitive Behavioral Therapy for Insomnia for Medical Residents [PDF]
Introduction: Cognitive behavioral therapy for insomnia (CBT-I) is a well-established nonpharmacological intervention that is the gold standard treatment for insomnia.
Chernyak, Yelena
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Structural competency in global perspective
This special issue aims to help fill two critical gaps in the growing literature as well as in practice. First, to bring together scholars and practitioners from around the world who develop, practice, review, and question structural competency with the ...
Carlos Piñones-Rivera +5 more
doaj +1 more source
The caring commodity : transformations in the exchange character of medicine in New Zealand (1840-1985) : a thesis presented to the Dept. of Geography, Massey University in complete fulfilment of the requirements for the degree of Master of Arts [PDF]
Retrospective analysis of actions and interactions connected with health care makes evident their place as constituted and constitutive components of capitalist social relations.
Hay, Iain Mill
core
Research on embedded counselling:an emerging topic of potential importance for the future of counselling psychology [PDF]
A significant proportion of the counselling that people receive takes place within informal, situated encounters between service users and practitioners in fields such as nursing, medicine, teaching and social work.
McLeod, John, McLeod, Julia
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Ambiguous Bodies, Biopower and the Ideologies of Science Fiction [PDF]
Contemporary Hollywood film narrates the fear of monstrous science; attending to the modulations of medicine, capital and the body. The filmic body is employed to illustrate the power of the new biotechnologies to create and sustain life and the new ...
Flynn, Susan
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

