Results 81 to 90 of about 1,502,953 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Estimation of the Risk of Developing Dysplastic Dependent Pathology of Bronchopulmonary System in Children Considering the Complex of Regional and Environmental as well as Social and Medical Factors

open access: yesGalician Medical Journal, 2016
Based on the study of the prevalence of potential risk factors the most informative ones were determined. Their prognostic value was used as a criterion for assessing the risk of developing dysplastic dependent pathology of the bronchopulmonary system in
A. F. Shypko
doaj  

Scarcity by design: famine, structural violence, and the biosocial inheritance of political deprivation

open access: yesFrontiers in Public Health
Famine is conventionally understood as a crisis of food supply, yet historical and contemporary evidence reveals it as a product of structural violence: political decisions, colonial extraction, and military force that manufacture scarcity and inscribe ...
Adan Eftekhari   +7 more
doaj   +1 more source

What kind of social protection for what kind of democracy? Dilemmas of social inclusion in Latin America

open access: yes, 2010
It is very moving to be part of this celebration of 25th anniversary of ALAMES, the Latin American Association of Social Medicine. These many years have been filled with dreams, struggles, warmth and emotion, debates, disappointments. and hopes.
Fleury, Sonia, Sonia Fleury
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

At Home With Medical Anthropology in the Former Yugoslavia

open access: yesSvetovi
The article traces the development of medical anthropology in the former Yugoslav region, highlighting how the discipline has evolved through the legacies of social medicine and socialist self-management and, in recent decades, as a response to ...
Tanja Bukovčan, Uršula Lipovec Čebron
doaj   +1 more source

Lehre am Puls der Zeit - Global Health in der Medizinischen Ausbildung: Positionen, Lernziele und methodische Empfehlungen [Cutting-Edge Education - Global Health in Medical Training: Prosposals, Educational Objectives and Methodological Recommendations]

open access: yesGMS Zeitschrift für Medizinische Ausbildung, 2009
[english] Aim: To formulate a guideline on educational objectives and methodology for the implementation of the cross-disciplinary subject “Global Health” in German medical education, on the initiative of the German Medical Students’ Association (bvmd ...
Bozorgmehr, Kayvan   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Global translation and adaptation of social medicines and structural competencies

open access: yesGlobal Public Health
This commentary on the special issue of Global Public Health on structural competency in global perspective asks: what is specific to the U.S. about structural competency, and what is its utility beyond the U.S., especially in the ‘global south’? Why are
Helena Hansen
doaj   +1 more source

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