Results 51 to 60 of about 212,164 (260)

Low physical activity is the strongest factor associated with frailty phenotype and frailty index: data from baseline phase of Birjand Longitudinal Aging Study (BLAS)

BMC Geriatrics, 2022
Background Frailty is the most complicated expression of aging that is related to disability or multi-morbidity. The aim of the present study was to estimate the prevalence of frailty and its associated factors among community-dwelling aged population ...
Ameneh Sobhani, Farshad Sharifi, Reza Fadayevatan, Ahmad Ali Akbari Kamrani, Mitra Moodi, Masoumeh Khorashadizadeh, Toba Kazemi, Huriye Khodabakhshi, Hossein Fakhrzadeh, Masoud Arzaghi, Seyedeh Zahra Badrkhahan, Raziye Sadat Hosseini, Hadi Monji, Amirabbas Nikkhah   +13 more
doaj   +1 more source

Social metabolism and bioeconomy Dialogue of knowledge

Apuntes de economía y sociedad, 2021
The general objective of the article is to characterize two analytical categories such as social metabolism and bioeconomy from the perspective of ecological economics as bridges for discussion, critique, and solution of the problems of the 21st century.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The coaching on lifestyle (CooL) intervention for obesity, a study protocol for an action-oriented mixed-methods study

BMC Public Health, 2018
Background Combined lifestyle interventions (CLIs) have proved to be effective in changing and maintaining behavioural lifestyle changes and reducing overweight and obesity, in clinical and real-world settings. In this CLI, lifestyle coaches are expected
Celeste E. van Rinsum, Sanne M. P. L. Gerards, Geert M. Rutten, Ien A. M. van de Goor, Stef P. J. Kremers   +4 more
doaj   +1 more source

Association of stress-related neural activity and baseline interleukin-6 plasma levels in healthy adults

Stress, 2022
Several studies suggest a link between acute changes in inflammatory parameters due to an endotoxin or (psychological) stressor and the brain’s stress response.
Johanna F. Voges, Laura Müller-Pinzler, Miriam Neis, Finn Luebber, Tanja Lange, Jennifer E. Hundt, Meike Kasten, Ulrike M. Krämer, Sören Krach, Lena Rademacher   +9 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Exacerbation of Hyperparathyroidism, Secondary to a Reduction in Kidney Function, in Individuals With Vitamin D Deficiency

Frontiers in Medicine, 2020
Aims/Introduction: Chronic kidney disease (CKD)-mineral and bone disorders (CKD-MBD) are an adverse outcome derived from decreases in kidney function, where abnormality of serum concentrations of calcium (Ca), phosphorus, parathyroid hormone (PTH), and ...
Makoto Daimon, Tomoyuki Fujita, Masaya Murabayashi, Satoru Mizushiri, Hiroshi Murakami, Yuki Nishiya, Jutaro Tanabe, Yuki Matsuhashi, Miyuki Yanagimachi, Itoyo Tokuda, Kaori Sawada, Kazushige Ihara   +11 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

International comparison of health care carbon footprints

Environmental Research Letters, 2019
Climate change confronts the health care sector with a dual challenge. Accumulating climate impacts are putting an increased burden on the service provision of already stressed health care systems in many regions of the world. At the same time, the Paris
Peter-Paul Pichler, Ingram S Jaccard, Ulli Weisz, Helga Weisz   +3 more
doaj   +1 more source