Results 41 to 50 of about 1,270,077 (292)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Horizontal mobility and possibilities of its actualization

Семиотические исследования
Social mobility in literature and scientific works is often associated with one of its sides - vertical mobility. Naturally, the issues related to the class structure of society and the change of status are of greater research interest than those focused
Denis N. Briket
doaj   +1 more source

Tracking pupil mobility over the pre-school and primary school period: evidence from EPPE 3-11 [PDF]

, 2008
This report describes the ‘tracking’ of the EPPE 3-11 sample and then goes on to examine the possible influence of mobility on EPPE 3-11 children’s cognitive progress and social/behavioural development over both the pre-school and primary school ...
Barreau, S., Hunt, S., Melhuish, Edward C., Sammons, P., Siraj-Blatchford, I., Sylva, K., Taggart, B., Welcomme, W.   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Navigating the future of transport infrastructure and governance

Energy, Sustainability and Society
The transformation of mobility and transport infrastructure is emerging as one of the defining societal challenges of the twenty-first century. This editorial introduces the Special Issue on “Sustainable Mobility Transitions: (New) Pathways of Future ...
Jörg Radtke, Weert Canzler
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Return migration and embedding: through the lens of Brexit as an unsettling event

Comparative Migration Studies
This introductory paper, reflecting the Thematic Cluster of four papers, brings together two themes that are important for migration studies: return migration and embedding.
Izabela Grabowska, Louise Ryan
doaj   +1 more source

Influence of gait-synchronized functional electrical stimulation during exoskeleton-assisted ambulation on cardiorespiratory outcomes in individuals with incomplete spinal cord injury

Journal of Rehabilitation Medicine
Objective: To evaluate the impact of gait-synchronized functional electrical stimulation during exoskeleton-assisted ambulation on cardiorespiratory demand in individuals with incomplete spinal cord injury.
Robert Voicu, Daniela B. Kuchen, Claudio Perret, Ines Bersch, Mario Widmer   +4 more
doaj   +1 more source