Results 41 to 50 of about 18,526 (265)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Georgia at the crossroads: for the analysis of social moods in the interelectoral period (2024-2025) [PDF]
Ante PortasThe paper aims at exploring and scrutinizing the mobility of the current social moods attributable to Georgia in one of its most determining times in the current history, i.e. in between two crucial elections – parliamentary elections of October 26, 2024,
Khatuna Chapichadze
doaj
Synesius, bishop of Ptolemais: Outline of the life and work [PDF]
Религия, церковь, общество, 2013 Synesius, bishop of Ptolemais, played an important role in the intellectual life of the Roman Empire on the turn of IV–V centuries. The article is devoted to the life and activity of Synesius in the context of his literary works that reflected the main ...
Olga Vladimirovna Przhigodzkaja
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Genres as Social Affect: Cultivating Moods and Emotions through Playlists on Spotify
Social Media + Society, 2019 This article bridges work on media technologies and affect theories through an analysis of how users appropriate playlists on Spotify. Our study draws on 30 interviews with users of music streaming services in Costa Rica and an analysis of their accounts
Ignacio Siles +3 more
doaj +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Ostium, 2019 Moods play a major role in Heidegger’s thought, as they open up the world to Dasein and permeate its entire existence, its possibilities of action, its very access to the world.
Beatrix Susanne Lepis
doaj
INTERVENTIONS IN SOCIAL NETWORKS: IMPACT ON MOOD AND NETWORK DYNAMICS [PDF]
Advances in Complex Systems, 2015 Results from two studies on longitudinal friendship networks are presented, exploring the impact of a gratitude intervention on positive and negative affect dynamics in a social network. The gratitude intervention had been previously shown to increase positive affect and decrease negative affect in an individual but dynamic group effects have not been
Danica Vukadinovic Greetham +3 more
openaire +4 more sources
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source