Results 81 to 90 of about 13,313,225 (361)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
Constructing, conducting and interpreting animal social network analysis
Summary Animal social networks are descriptions of social structure which, aside from their intrinsic interest for understanding sociality, can have significant bearing across many fields of biology.
D. Farine, H. Whitehead
semanticscholar +1 more source
Quantification in social networks
In many real-world applications there is a need to monitor the distribution of a population across different classes, and to track changes in this distribution over time. As an example, an important task is to monitor the percentage of unemployed adults in a given region.
Milli L+5 more
openaire +4 more sources
The pneumococcal social network
Gram-positive bacteria employ an array of secreted peptides to control population-level behaviors in response to environmental cues. We review mechanistic and functional features of secreted peptides produced by the human pathogen Streptococcus pneumoniae.
Surya D. Aggarwal+3 more
openaire +4 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
In knowledge management (KM), one perspective is that knowledge resides in individuals who interact in groups. Concepts as communities-of-practice, knowledge networks, and “encultured knowledge” as the outcome of shared sense-making (Blackler, 1995) are built upon this perspective.
Dekker, D.J., Hendriks, P.H.J.
openaire +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
The Imagined Audience on Social Network Sites
When people construct and share posts on social network sites like Facebook and Twitter, whom do they imagine as their audience? How do users describe this imagined audience? Do they have a sub-audience in mind (e.g., “friends who like reality television”
E. Litt, E. Hargittai
semanticscholar +1 more source
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki+4 more
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source