Results 121 to 130 of about 15,488,054 (294)

A Study on Health Nutrition Obsession, Social– Physique Anxiety, and Social Media Addiction of Young Individuals

The objective of this research is to explore the connections between preoccupation with healthy dietary habits, social physical apprehension, and addiction to social networking platforms among young people.
Merve Kişi, Selin Kalender
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Development and Validation of the Short-Form Drama Addiction Motivation Scale: A Network Analysis Approach

Acta Psychologica
This study aimed to develop and validate a Short-Form Drama Addiction Motivation Scale using network analysis to better understand the factors underlying short-form drama addiction. A sample of 625 Chinese university students completed a survey including
Shijie Guo, Yanchao Yang, Tianxue Cui, Zehan Tan, Xinxin Yang, Wangze Li   +5 more
doaj   +1 more source

The Relationship of Mobile-Based Social Network Addiction and Family Communication Patterns, with Behavioral Problems in Secondary School Students: The Mediating Role of Emotional Self-Regulation. [PDF]

Psychol Russ, 2023
Fasihi M, Rostami M.
europepmc   +1 more source

The impact of social comparison, FoMo, cyberbullying, and social media addiction on social anxiety among Malaysian youth [PDF]

This study explores the relationship between social comparison, Fear of Missing Out (FoMO), cyberbullying, social media addiction, and social anxiety among Malaysian youth.
Kunhao, Zhang, Ma’rof, Aini Azeqa, Dahamat Azam, Mohamad Naqiuddin   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Social network addiction symptoms and body dissatisfaction in young women: exploring the mediating role of awareness of appearance pressure and internalization of the thin ideal. [PDF]

J Eat Disord, 2022
Delgado-Rodríguez R, Linares R, Moreno-Padilla M.   +2 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Network analysis of peer attachment and internet addiction among chinese adolescents

Scientific Reports
Previous studies have found a correlation between peer attachment and Internet addiction. The three dimensions (peer trust, peer communication, and peer alienation) of peer attachment reflect different needs in peer relationships. This study used network
Xinyi Feng, Wenhe Wang, Jie Luo, Jie Zhang, Chang Peng, Qin Liu   +5 more
doaj   +1 more source