Results 141 to 150 of about 15,488,054 (294)

Factors influencing internet addiction among university students: The mediating roles of self-control and anxiety

Acta Psychologica
This study aims to explore the key factors affecting internet addiction among college students, analyzing how stress, social support, self-efficacy, self-control, and anxiety influence internet addiction and their interrelationships and mechanisms.
Man Chen, Xinyu Zhang
doaj   +1 more source

A Theory of Natural Addiction [PDF]

Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Tasnadi, Attila, Smith, Trenton G.
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The interaction between problematic internet use, diet quality, and disordered eating risk in adolescents: a mediation and network analysis

Eating and Weight Disorders
Background Adolescence is a key period for problematic internet use (PIU) and disordered eating (DE), with prior studies linking them, but the role of diet quality unclear.
Mevra Aydin Cil, Sumeyye Carikci, Elham Foroudi Pourdeh, Haitham Jahrami   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Stress-coping mechanisms and problematic social media use: A network analysis and differences across men and women

Computers in Human Behavior Reports
Background: Problematic Social Media Use (PSMU) affects up to 40 % of users globally and disproportionately impacts women. While conceptual ambiguity remains in relation to PMSU, evidence suggests social media is frequently engaged as a coping strategy ...
Connor Conkey-Morrison, Daniel Zarate, Evita March, Brian Hunt, Vasileios Stavropoulos   +4 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Addiction is one of the social problems which has a significant role in the spiritual and physical health of the person, family

Research on Addiction, 2009
Addiction is one of the social problems which has a significant role in the spiritual and physical health of the person, family, and specially the health of the society.
Fereshte Jaliliyan
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source