Results 151 to 160 of about 15,488,054 (294)

British journal of addiction.

open access: yes, 1903
Contains papers read at the quarterly meetings of the society, and extracts from the discussions following them with other communications dealing with alcohol and alcoholism.Title varies slightly.Title from cover.None published July-Dec.
Society for the Study of Addiction to Alcohol and Other Drugs.   +1 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

The YouTube Addiction Scale : Psychometric Evidence for a New Instrument Developed Based on the Component Model of Addiction

open access: yes
Technological advances have created the environment for Internet addiction (IA). A specific form of IA is social media addiction. Moreover, social media addiction may be further classified into general or specific social media addiction, with YouTube ...
Jafari, Elahe,   +4 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

The Role of Internet Addiction in Social Health

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2019
- Aim and Background: Given the dangerous consequences that addiction to the internet has for adolescent individuals, the issue of internet addiction and its implications for the individual, family and social life of a teenager is important.
Ayatollah Fathi   +4 more
doaj  

Addiction and Self-Control: An Intrapersonal Game [PDF]

open access: yes
In their model of addiction, O´Donoghue and Rabin obtain a counterintuitive result: a person that is fully aware of his self-control problems (sophisticate) is more prone to become addicted than one who is fully naware (na¨ıf).
López Rafael
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Inventory for Social Network Addiction

open access: yesJournal of Addiction Research & Therapy, 2018
Md Suhail Jogi   +2 more
openaire   +1 more source

Is Addiction "Rational"? Theory and Evidence [PDF]

open access: yes
A standard model of addictive process is Becker and Murphy's rational addiction' model, which has the key empirical prediction that the current consumption of addictive goods should respond to future prices, and the key normative prediction that the ...
Jonathan Gruber, Botond Koszegi
core  

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