Results 81 to 90 of about 14,102,468 (353)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Social Network Modeling

open access: yesAnnual Review of Statistics and Its Application, 2018
The development of stochastic models for the analysis of social networks is an important growth area in contemporary statistics. The last few decades have witnessed the rapid development of a variety of statistical models capable of representing the global structure of an observed network in terms of underlying generating mechanisms.
Amati, Viviana   +2 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Problematic use of social networking sites among urban school going teenagers

open access: yesIndustrial Psychiatry Journal, 2012
Background: Social networking sites like Facebook, Orkut and Twitter are virtual communities where users can create individual public profiles, interact with real-life friends and meet other people based on shared interests.
Parth Singh Meena   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The SNAP Platform: social networking for academic purposes [PDF]

open access: yes, 2010
Purpose The paper introduces an enterprise-wide Web 2.0 learning support platform—SNAP—developed at Victoria University in Melbourne, Australia.
Kirkwood, Keith   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Exploring the Perceptions and Usage of Social Networking Sites among Distance Learning Students in Nigeria

open access: yesWest African Journal of Open and Flexible Learning, 2016
Social networking sites have become popular virtual meeting places that allow young adults to interact and socialize with their peers. This study was carried out to investigate the perceptions and usage of social networking sites among distance learning
Chibuogwu V. Nnaka
doaj  

Impact of Social Networking Sites on Academic Performance of University Students: A Quantitative Analysis

open access: yesReviews of Management Sciences, 2021
Purpose: The aim of this research study is to examine the possible impact of social networking sites on the academic performance of university students. The rationale behind the study is to find out whether the daily exposure of the students to social
Muhammad Asad Ullah   +5 more
doaj  

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