Results 91 to 100 of about 479,984 (317)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
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Risks and Threats of Social Networks Communication
Communications, 2014 This paper focuses on social networks as a source of information and a tool for its sharing. The first part of the paper defines the theoretical background while the second part is devoted to the evaluation of research which was conducted among ...
Jan Zavodny Pospisil, Lucie Sara Zavodna
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
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The Social Responsibility of a Social Network
Voices in Bioethics, 2014 You may have participated in a published research study without even knowing it. In 2012, Facebook ran an experiment on almost 700,000 users wherein their emotions were manipulated without the participants knowing they enrolled in the study. After the paper was published, many users inquired as to when they gave consent to participate in the study ...
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Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
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Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
Procedia - Social and Behavioral Sciences, 2011 AbstractIn the past decade Social Network Analysis (SNA) has become an established research field in the social and behavioral sciences as well as the natural sciences. The international conference on Applications of Social Network Analysis (ASNA) brings this interdisciplinary community together to assess the state of the field and discuss current ...
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Attempted suicide in social networks. [PDF]
, 1969 Norman Kreitman, P Smith, Eng-Seong Tan
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
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Revista de Administração, 2016 Individuals often base their decisions on what they observe in their neighborhood or peer groups. It can be, on the one hand, that individuals gather information from their peers’ experiences: for example, a consumer will be more likely to adopt a given product if many of that consumer’s friends report a positive experience with the product.
Goyal, Sanjeev, Gagnon, Julien
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