Results 91 to 100 of about 15,435,726 (351)

Dynamics in online social networks

, 2012
An increasing number of today's social interactions occurs using online social media as communication channels. Some online social networks have become extremely popular in the last decade.
A. Lancichinetti, A. Mislove, A. Mislove, A. Saichev, A. Vespignani, A.-L. Barabási, A.-L. Barabási, B. Söderberg, B. Viswanath, B.A. Huberman, C. Honeycutt, C. Wilson, D. Centola, D. Centola, D. Centola, D. Centola, D. Foster, D. Garlaschelli, D. Lazer, D. Taraborelli, D.J. Watts, D.J. Watts, E. Bakshy, E. Eisenberg, G. Bianconi, G. Caldarelli, G. Masi De, G. Palla, G. Zipf, H. Chun, H. Ebel, H.-B. Hu, H.A. Simon, J. Leskovec, J. Leskovec, J. Leskovec, J. Leskovec, J. Ratkiewicz, J. Travers, J.-P. Onnela, J.L. Iribarren, J.N. Cummings, J.S. Kong, K. Yamasaki, L.A. Adamic, M. Boguñá, M. McPherson, M. Newman, M. Newman, M. Newman, M.E.J. Newman, M.S. Granovetter, P.A. Grabowicz, P.A. Grabowicz, P.V. Marsden, R. Burt, R. Guimerà, R. Schifanella, S. Aral, S. Boccaletti, S. Bornholdt, S. Fortunato, S.N. Dorogovtsev, T. Opsahl, V. Pareto, Y.Y. Ahn   +65 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Immigration from the Immigrants’ Perspective: Analyzing Survey Data Collected among Immigrants and Host Society Members

Social Inclusion, 2019
Immigration has been one of the most crucial global phenomena, changing the fabric of many societies, and a topic of substantial research. Much of this research has focused on how the host society views immigrants and immigration, or on the societal ...
Alice Ramos, Eldad Davidov, Peter Schmidt, Marta Vilar Rosales, Dina Maskileyson   +4 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

The diplomat's dilemma: Maximal power for minimal effort in social networks

, 2008
Closeness is a global measure of centrality in networks, and a proxy for how influential actors are in social networks. In most network models, and many empirical networks, closeness is strongly correlated with degree.
A Barrat, D Kahneman, D Knoke, DJ Watts, G Ehrhardt, G Sabidussi, K Lindgren, K Nakao, LM Valen van, M Nowak, M Rosvall, M Rosvall, M Weber, MA Nowak, MEJ Newman, MO Jackson, P Erdős, P Holme, P Holme, P Holme, PW Holland, R Albert, R Axelrod, S Gila, SN Dorogovtsev, T Gross, V Bala   +26 more
core   +1 more source

Do online social media cut through the constraints that limit the size of offline social networks?

Royal Society Open Science, 2016
The social brain hypothesis has suggested that natural social network sizes may have a characteristic size in humans. This is determined in part by cognitive constraints and in part by the time costs of servicing relationships.
Robin I. M. Dunbar
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source