Results 81 to 90 of about 14,746,680 (258)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Social networks [PDF]

open access: yes, 2014
Social networks affect individual behavior as well as social phenomena. Conversely, when actors can choose with whom to interact, social networks are also themselves affected by individual behavior.
Raub, Werner   +7 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Anonymizing Social Networks [PDF]

open access: yes, 2007
Advances in technology have made it possible to collect data about individuals and the connections between them, such as email correspondence and friendships.
Philipp Weis   +9 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Social enterprise networks and social capital: A case study in Scotland/UK [PDF]

open access: yes, 2014
The chapter focuses on how social aims and cooperative attitudes have been supported in the shaping of networks in Scotland, and why this is relevant for the sustainable development of social enterprise and communities. From this background, our main aim
Campbell, Colin, Sacchetti, Silvia
core  

Enhancing Social Networks with Agent and Semantic Web Technologies

open access: yes, 2012
In this chapter, the authors describe the relationships between multi-agent systems, social networks, and the Semantic Web within collaborative work; they also review how the integration of multi-agent systems and Semantic Web technologies and techniques
Agostino Poggi   +5 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Consumer-Centric Protection for Online Social Networks [PDF]

open access: yes, 2014
Online Social Networks (OSNs) are a unique construct that is shaped by the advancement and availability of Internet technologies. A large portion of internet users make use of OSN services to share and celebrate their personal lives with friends and ...
Tsz Fung Law   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy