Results 121 to 130 of about 15,667,104 (396)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Dynamics in online social networks

open access: yes, 2012
An increasing number of today's social interactions occurs using online social media as communication channels. Some online social networks have become extremely popular in the last decade.
A. Lancichinetti   +65 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Risks and Threats of Social Networks Communication

open access: yesCommunications, 2014
This paper focuses on social networks as a source of information and a tool for its sharing. The first part of the paper defines the theoretical background while the second part is devoted to the evaluation of research which was conducted among ...
Jan Zavodny Pospisil, Lucie Sara Zavodna
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Forecasting national CO2 emissions worldwide

open access: yesScientific Reports
Urgent climate action, especially carbon emissions reduction, is required to achieve sustainable goals. Therefore, understanding the drivers of and predicting $$\hbox {CO}_2$$ emissions is a compelling matter.
Lorenzo Costantini   +4 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

A shape-based heuristic for the detection of urban block artifacts in street networks

open access: yesJournal of Spatial Information Science
Street networks are ubiquitous components of cities, guiding their development and enabling movement from place to place; street networks are also the critical components of many urban analytical methods.
Martin Fleischmann, Anastassia Vybornova
doaj   +1 more source

Exploring Text Virality in Social Networks

open access: yes, 2011
This paper aims to shed some light on the concept of virality - especially in social networks - and to provide new insights on its structure. We argue that: (a) virality is a phenomenon strictly connected to the nature of the content being spread, rather
Guerini, Marco   +2 more
core   +1 more source

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