Results 61 to 70 of about 15,435,726 (351)

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Detecting Community Structure in Dynamic Social Networks Using the Concept of Leadership

open access: yes, 2017
Detecting community structure in social networks is a fundamental problem empowering us to identify groups of actors with similar interests. There have been extensive works focusing on finding communities in static networks, however, in reality, due to ...
A Clauset   +18 more
core   +1 more source

Dynamics of private social networks [PDF]

open access: yes, 2014
Social networks, have been a significant turning point in ways individuals and companies interact. Various research has also revolved around public social networks, such as Twitter and Facebook.
Mifsud, Jonathan, Montebello, Matthew
core   +1 more source

The role of social networks in information diffusion [PDF]

open access: yesThe Web Conference, 2012
Online social networking technologies enable individuals to simultaneously share information with any number of peers. Quantifying the causal effect of these mediums on the dissemination of information requires not only identification of who influences ...
E. Bakshy   +3 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

MOBILE TIME AS A BLESSING OR A CURSE: PERCEPTIONS OF SMARTPHONE USE AND PERSONAL TIME AMONG GENERATION GROUPS IN ESTONIA; pp. 45–62 [PDF]

open access: yesTrames, 2018
Although the literature has paid a lot of attention to the importance of mobile digital media in shaping people’s perception of personal and social time, little empirical research has focused on these issues.
Veronika Kalmus   +3 more
doaj   +1 more source

Data Journalism and Network Theory: A Study of Political Communication through X (Formerly Twitter) Interactions

open access: yesJournalism and Media, 2023
This study investigates the research questions: “How do political connections within Greece’s governing party evolve, and what underlying patterns and dynamics are revealed through a network analysis of interactions on X (formerly Twitter)?” To address ...
Alexandros Samalis   +8 more
doaj   +1 more source

Interests Diffusion in Social Networks

open access: yes, 2015
Understanding cultural phenomena on Social Networks (SNs) and exploiting the implicit knowledge about their members is attracting the interest of different research communities both from the academic and the business side.
D'Agostino, Gregorio   +3 more
core   +1 more source

Choosing Products in Social Networks [PDF]

open access: yes, 2012
We study the consequences of adopting products by agents who form a social network. To this end we use the threshold model introduced in Apt and Markakis, arXiv:1105.2434, in which the nodes influenced by their neighbours can adopt one out of several ...
Apt, Krzysztof R., Simon, Sunil
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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