Results 201 to 210 of about 7,916,499 (329)

Strategies for community-sourced biocuration in bioinformatics: a case study on MIBiG 4.0. [PDF]

Brief Bioinform
Blin K, Loureiro C, Louwen NLL, Navarro-Muñoz JC, Gerstmans H, Robinson SL, Rutz A, Reitz ZL, Doering DT, van der Hooft JJJ, Weber T, Medema MH, Zdouc MM.   +12 more
europepmc   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

ChEBI: re-engineered for a sustainable future. [PDF]

Nucleic Acids Res
Malik A, Arsalan M, Moreno C, Mosquera J, Félix E, Kizilören T, Muthukrishnan V, Zdrazil B, Leach AR, O'Boyle NM.   +9 more
europepmc   +1 more source

Some Critical Issues in Social Ontology: Reply to John Searle

, 2016
T. Lawson
semanticscholar   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Unlocking the power of groups in youth sport: a proof-of-concept evaluation of the Together For Us (T4Us) intervention. [PDF]

Pilot Feasibility Stud
Bruner MW, McLaren CD, Schertzinger M, Boardley ID, Martin LJ, Slatcher RB, Vella S, Carré JM, Fransen K.   +8 more
europepmc   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Three-layered semantic framework for public health intelligence. [PDF]

J Biomed Semantics
Guru Rao S, Rokkam P, Zhang B, Sargsyan A, Kaladharan A, Sethumadhavan P, Jacobs M, Hofmann-Apitius M, Tom Kodamullil A.   +8 more
europepmc   +1 more source

Comparing Conceptions of Social Ontology: Emergent Social Entities and/or Institutional Facts?

, 2016
T. Lawson
semanticscholar   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source