Graphene Oxide-Induced Toxicity in Social Insects: Study on Ants Through Integrated Analysis of Physiology, Gut Microbiota, and Transcriptome. [PDF]
Lei T, Wang Z, Wang X, Zhao S, Duo L.
europepmc +1 more source
PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa +23 more
wiley +1 more source
AgBioDatabase Finder: an online tool to help researchers find and submit agricultural genomic, genetic, and breeding data. [PDF]
Cabugos L +10 more
europepmc +1 more source
CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan +21 more
wiley +1 more source
LLM-supported collaborative ontology design for data and knowledge management platforms. [PDF]
Kampars J +4 more
europepmc +1 more source
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir +7 more
wiley +1 more source
Human Dignity and the Metaphysical Crisis in Postmodern Ethics. [PDF]
Frantz P, Rego F, Barbas S.
europepmc +1 more source
Cambridge social ontology: an interview with Tony Lawson [PDF]
DesRoches, C. Tyler, Lawson, Tony
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