Results 151 to 160 of about 60,902 (257)
Advanced Science, EarlyView.Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo +5 more
wiley +1 more source
Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation
Advanced Science, EarlyView.Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir +3 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li +9 more
wiley +1 more source
The SPC model as a heuristic tool to better understand autism spectrum disorder and other structural diagnosis in psychiatry and psychotherapy. [PDF]
Front PsychiatryTebartz van Elst L.
europepmc +1 more source
Advanced Science, EarlyView.Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao +7 more
wiley +1 more source
Impact of Self-Efficacy and Self-Esteem on Caregiver Burden in Formal and Informal Caregivers of People with Dependency: A Systematic Review. [PDF]
Healthcare (Basel)Andrés-Pérez F +3 more
europepmc +1 more source
Degradation Pathways of Silicon‐Based Anodes in Lithium‐Ion Batteries
Advanced Energy Materials, EarlyView.Silicon‐based anodes undergo degradation through five primary pathways: (1) mechanical and structural deterioration of the active material, (2) loss of electrode integrity and electrical contact, (3) mechanical instability of the solid electrolyte interphase (SEI), characterized by repetitive fracture and deformation, (4) chemical instability of the ...
Yoon Jeong Choi +3 more
wiley +1 more source
Work Role Overload and Employee Time Theft: A Daily Diary Examination of JD-R Pathways via Fatigue and Intrinsic Motivation. [PDF]
Int J PsycholGoyal R, Sekhar C.
europepmc +1 more source
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT To increase farmer adoption of green practices, the EU Common Agricultural Policy includes both mandatory (conditionality) and voluntary instruments (eco‐schemes–ECS– and more demanding, multi‐annual agri‐environment‐climate measures –AECM–). Building on the experiment of Barreiro‐Hurle et al.
L. Sanchez‐Mata +4 more
wiley +1 more source
How enterprise social media use affects employee well-being. [PDF]
Sci RepSong DE, Kim S.
europepmc +1 more source