Results 31 to 40 of about 60,902 (257)

A systematic investigation of the relationship between social media overuse, cognitive overload, and digital burnout among university students in the United Arab Emirates [PDF]

International Journal of Data and Network Science
This study investigates the impact of social media overuse, fear of missing out, and notification overload on digital burnout among university students in the United Arab Emirates, with a particular focus on the mediating role of cognitive ...
Abdullah Mohammad Bani-Rshaid, Suad Abdalkareem Alwaely, Mervat Jaser Ahmad, Hamda Saeed Almazrouei, Ghubaisha Rashed Almansoori, Eiman Hasan Aldhuhoori, Alya Khamis Aldahmani   +6 more
doaj   +1 more source

Exploring discontinuous intentions of social media users: a cognition-affect-conation perspective

Frontiers in Psychology
IntroductionDrawing on the cognition-affect-conation (C-A-C) framework, this study investigates how perceived information and social and system feature overload induce depression and anxiety, which leads to affect discontinuous intentions of the social ...
Sara Qaisar, Anum Nawaz Kiani, Afsheen Jalil   +2 more
doaj   +1 more source

An Overview of Information Overload, System Feature Overload, Social Overload and Communication Overload

Environment-Behaviour Proceedings Journal
Social media has faced difficulties in recent years due to users ceasing to use them, but little is known about the relationships between the various aspects of overload and how this negatively impacts users' social media exhaustion. Additionally, it described social media overload as a multidimensional construct made up of four types of overloads ...
Muhammad Danish Noor Azri, Siti Nadia Nadirah Abdull Malek, Tuan Badrol Hisham Tuan Besar   +2 more
openaire   +1 more source

Investigating the factors of enterprise social media strain: The role of enterprise social media's visibility as a moderator.

PLoS ONE, 2022
The significant effect of enterprise social media (ESM) usage has been extensively researched. However, recent studies and analysis have also emphasized the importance of understanding the negative aspects of ESM's use.
Ying Li, Abdul Hameed Pitafi, Haoning Li
doaj   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The influence of social media news overload on news avoidance and filtering in Generation Z: A PLS-SEM study [PDF]

World of Media
This study examines the influence of social media news overload on the news consumption behaviors of Generation Z users in Vietnam, emphasizing the roles of news efficacy, affective load, and social filtering.
Le Dinh Hai, Xiao Yan Xiong
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Work overload and addictive social media use [PDF]

, 2022
Work overload is highly related to mental health issues. Online social media are often used to escape the feelings of overload. In the current study, 291 employees from various job sectors completed an online survey related to work overload, addictive social media use (SMU), and mental health (i.e., depression symptoms, life satisfaction).
Brailovskaia, Julia (PD Dr.), Frahsek, Marc (M. Sc.), Margraf, Jürgen (Prof. Dr.)   +2 more
openaire