Results 121 to 130 of about 3,883,150 (311)

Development of a prediction model for identifying older adults with low protein using a simple food intake questionnaire

open access: yesJournal of Nutritional Science
Adequate protein intake is crucial for preventing frailty and sarcopenia in older adults, but conventional dietary assessments are time-consuming. Developing a rapid screening tool for identifying those at risk of low protein intake is essential; however,
Yuri Yokoyama   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Labor Migration and Social Networks Participation: Evidence from Southern Mozambique [PDF]

open access: yes
This paper investigates how social networks in poor developing settings are af- fected if people migrate. By using an unique household survey from two southern regions in Mozambique, we test the role of labor mobility in shaping participation in groups ...
Juan M. Gallego, Mariapia Mendola
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Dose–response associations between physical activity and sedentary time with functional disability in older adults with or without frailty: a prospective cohort study

open access: yesFrontiers in Public Health
PurposeEvidence regarding the dose–response curve shapes of physical activity (PA) and sedentary time (ST) in older adults with functional disability (FD) is extremely limited. Moreover, these associations may differ depending on with/without frailty. We
Satoshi Seino   +8 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Why don’t people do what’s good for them? : an examination of the value(s) which affect physical activity. [PDF]

open access: yes, 2012
One of the 21st Century’s major public health issues is physical inactivity. Therefore one of the greatest public policy challenges is to find new ways of conferring to an inactive population the health related benefits that arise from being physically ...
Kearns, PJ   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Relationship Between Organization in Time, Executive Functions, and Quality of Life in Adult ADHD

open access: yesBrain Sciences
Background/Objectives. Despite the importance of organization-in-time ability for adults’ daily performance, knowledge about this ability in adults with attention-deficit/hyperactivity disorder (ADHD) remains limited.
Nufar Grinblat, Sara Rosenblum
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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