Results 111 to 120 of about 1,688,073 (307)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Multi-Country Study on Trusted Partners among Youth: Eritrea, Tanzania, Zambia, and Zimbabwe [PDF]

open access: yes, 2002
ObjectivesExplore youth's definitions of "trust"Establish criteria youth use to determine the trustworthiness of partnersIdentify types of individuals youth believe they can and cannot "trust"Examine trust's influence on sexual decision-making and STI ...
John Berman, Kim Longfield, Megan Klein
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

ASPIRASI MITRA DRIVER DALAM KAMPANYE GOJEK INDONESIA (ANALISIS ISI KOLOM KOMENTAR KAMPANYE DI AKUN INSTAGRAM @gojekindonesia) [PDF]

open access: yes
In marketing products and building a positive image of the company, GoJek Indonesia uses marketing campaigns uploaded to the Instagram social media account @gojekindonesia.
Dahliani, Ersa Kartika
core  

Information-Sharing and Privacy in Social Networks [PDF]

open access: yes, 2010
We present a new model for reasoning about the way information is shared among friends in a social network, and the resulting ways in which it spreads. Our model formalizes the intuition that revealing personal information in social settings involves a ...
Kleinberg, Jon, Ligett, Katrina
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Healthcare workers’ views on decentralized primary health care management in Lesotho: a qualitative study

open access: yesBMC Health Services Research
Background Lesotho experienced high rates of maternal (566/100,000 live births) and under-five mortality (72.9/1000 live births). A 2013 national assessment found centralized healthcare management in Ministry of Health led to fragmented, ineffective ...
Ermyas Birru   +13 more
doaj   +1 more source

Health worker attrition at a rural district hospital in Rwanda: a need for improved placement and retention strategies

open access: yesThe Pan African Medical Journal, 2017
INTRODUCTION: the shortage and maldistribution of health care workers in sub-Saharan Africa is a major concern for rural health facilities. Rural areas have 63% of sub-Saharan Africa population but only 37% of its doctors.
Jackline Odhiambo   +7 more
doaj   +1 more source

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