Results 121 to 130 of about 1,688,073 (307)

Efficiency of application of innovative technologies in the organization of practical training

open access: yesОткрытое образование (Москва), 2019
The article discusses the effectiveness of creating a network site as a mechanism to ensure the quality of training, allowing to introduce innovative and practical activities in the educational process, developing the scientific potential of educational ...
N. I. Taraseeva, O. V. Baulina
doaj   +1 more source

SOCIAL WORK: A SOCIAL PARTNER IN ECONOMIC DEVELOPMENT

open access: yesSocial Work/Maatskaplike Werk, 2014
Like many other countries worldwide, South Africa has accepted the challenge to achieve theaim of the United Nations to alleviate poverty by half by the year 2015. Thin (2002:17) statesthat poverty is a clear indicator that an economic system is not working as well as it should.
openaire   +3 more sources

Cross-Generational Relationships in Kenya: Couples' Motivations, Risk Perception for STIs/HIV and Condom Use [PDF]

open access: yes, 2003
Objectives: To understand women's and men's motivations for entering into cross-generational relationships and to examine how their risk perception for sexually transmitted infections (STIs) and human immunodeficiency virus (HIV) affects sexual decision ...
Anne Glick   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Allies Not Adversaries: Teaching Collaboration to the Next Generation of Doctors and Lawyers to Address Social Inequality [PDF]

open access: yes, 2008
Recent reports from the Carnegie Foundation for the Advancement of Teaching, as well as from other medical and legal educators, stress that professional training of doctors and lawyers focuses too narrowly on knowledge-based learning, and not enough on ...
Tyler, Elizabeth Tobin
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Unveiling the effects of nonviolent communication training on youth empathy

open access: yesSocial Welfare: Interdisciplinary Approach
Nonviolent communication (NVC) is a model of communication approach, a method, a process, a mindset and a way of life, and was developed by Marshal Rosenberg. NVC offers tools that support the principle of nonviolence and empathic communication.
Aistė Batūraitė-Bunka   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Evaluation of Sure Start Mellow Valley: Findings from the stakeholder survey [PDF]

open access: yes, 2005
Sure Start is a government programme which aims to make a difference to children 0-4 years and their families through supporting parents, increasing childcare availability and improving the health and social development of young children.
Newell, C, South, J, Walker, J
core  

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