Results 61 to 70 of about 266,407 (215)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Social partners and social security systems
, 2007 The unemployment benefit systems were established at quite different times in the various European countries. In the new Member States, these systems are a fairly recent phenomenon. In some countries, the role of employees and employers in the system has remained of major importance, while in others this function has partly or fully been taken over by ...
Schaapman, M., van het Kaar, R.
openaire +1 more source
Do People Regard Robots as Human-Like Social Partners? Evidence From Perspective-Taking in Spatial Descriptions. [PDF]
Front Psychol, 2020 Xiao C, Xu L, Sui Y, Zhou R.
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Leisure activity in middle-aged adults with Down syndrome: Initiators, social partners, settings and barriers. [PDF]
J Appl Res Intellect Disabil, 2020 Mihaila I +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The smell of hunger: Norway rats provision social partners based on odour cues of need. [PDF]
PLoS Biol, 2020 Schneeberger K, Röder G, Taborsky M.
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Social mobility and partnering
Does the experience of social mobility influence one's choice of a partner? If so, are the socially mobile more likely to partner with someone from their origin or destination class? Or, if torn between the familiarity of their origin milieu and their possibly less known destination, do they opt for 'mobility homogamy', i.e.
Esping-Andersen, Gosta|| +2 more
openaire +1 more source