Results 81 to 90 of about 12,430,753 (309)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Recruitment Questionnaire 2024

open access: yes
Pseudonymized survey microdata from the 2024 Recruitment Questionnaire of The Social Study (TSS) — a probability-based panel survey of individuals aged 16+ residing in private households in Belgium.
The Social Study, TSS
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Maternal mortality and the metempsychosis of user fees in Liberia: A mixed-methods analysis

open access: yesScientific African, 2019
: Liberia, a country recently afflicted by civil conflict and an epidemic of Ebola virus disease, has one of the highest rates of maternal mortality in the world. A biosocial analysis of this problem can help identify and address barriers impeding access
Elsie G. Karmbor-Ballah   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Hiland Partners Holdings LLC Bakken Missouri River Crossing Project: Biological assessment

open access: yes, 2019
Hiland Partners Holdings LLC Bakken Missouri River Crossing Project Biological Assessment PRESENTED BY MERJENT, INC. March 25, 2019 mr.erjent HILAND PARTNERS HOLDINGS LLC BAKKEN MISSOURI RIVER CROSSING PROJECT BIOLOGICAL ASSESSMENT i TABLE OF CONTENTS ...
Hiland Partners Holdings LLC
core  

A comprehensive district-level laboratory intervention after the Ebola epidemic in Sierra Leone

open access: yesAfrican Journal of Laboratory Medicine, 2019
Background: The 2014–2016 Ebola outbreak exposed the poor laboratory systems in Sierra Leone. Immense needs were recognised across all areas, from facilities, diagnostic capacity, supplies, trained personnel to quality assurance mechanisms.
Annelies W. Mesman   +7 more
doaj   +1 more source

Semantic systems are mentalistically activated for and by social partners. [PDF]

open access: yesSci Rep, 2022
Forgács B   +6 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Franklin County, Ohio, immigrants and refugees a profile of the population, resources, and services

open access: yes, 2005
Title from PDF cover (viewed on June 20, 2008); "December 2005."; Includes bibliographic references (p.
Community Research Partners.
core  

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