Results 191 to 200 of about 1,251,629 (312)

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Reciprocal innovation in implementation science and global health: reflections from the EXTRA-CVD (extending the HIV treatment cascade for cardiovascular disease prevention) study. [PDF]

BMC Glob Public Health
Leung CL, Bosworth HB, Webel AR, Aifah A, Akwanalo C, Bloomfield GS, Choi EW, Gripshover BM, Hileman CO, Kamano J, Lopez-Kidwell V, Muiruri C, Njuguna B, Okeke NL, Longenecker CT, Vedanthan R.   +15 more
europepmc   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Addressing Precarious Work Through Policy and Systems Change: A Case of a Local Health Department, University, and Worker Center Collaboration in Suburban Cook County, IL. [PDF]

J Public Health Manag Pract
Jarpe-Ratner E, Fisher L, Bonney T, Pinsker E, Kader A, Bell T, Rodriguez C, Barnett GM, Rubin R, Welter C.   +9 more
europepmc   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

Proposal for a new conceptual framework to guide early intervention professionals in a transcultural context. [PDF]

Front Public Health
Elias B, Bogossian A.
europepmc   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

Advanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti, Salma Mansi, Dominic Biebl, Malin Reuter, Maximilian Grab, José Carlos Rodríguez‐Cabello, Petra Mela   +6 more
wiley   +1 more source

Setting research priorities for palliative and end-of-life care: a James Lind Alliance Priority Setting Partnership Refresh. [PDF]

BMJ Open
Hudson BF, Ashcroft P, Bedford J, Bush J, Bowers B, Dawson A, Hussain J, Holmes S, Kumar R, Minton O, McCullagh A, Nicoll L, Penny A, Rabbitte M, Reece A, Robinson D, Simpson-Greene C, Taylor M, Best SL.   +18 more
europepmc   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Resilience and post-traumatic stress symptoms in grandparents following their grandchild's cancer diagnosis from a multicenter cohort study in Switzerland (The GROKids project). [PDF]

Discov Oncol
Raguindin PF, Maas A, Ilic A, Priboi C, Roser K, Farrag A, Schilling F, Tanriver U, Diesch-Furlanetto T, Scheinemann K, Michel G.   +10 more
europepmc   +1 more source