Results 141 to 150 of about 296,086 (336)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Contribution of lipophilicity to the clinical effects of drugs

Российский кардиологический журнал
The article is devoted to a detailed analysis of the action of various drugs used in the treatment of hypertension and atherogenic dyslipidemia, depending on their ability to dissolve in fatty media (lipophilicity). The authors analyze connection between
A. S. Skotnikov, M. V. Melnik, E. A. Zinina, I. V. Sivertseva   +3 more
doaj   +1 more source

Simple pain measures reveal psycho-social pathology in patients with Crohn's disease. [PDF]

World J Gastroenterol, 2017
Odes S, Friger M, Sergienko R, Schwartz D, Sarid O, Slonim-Nevo V, Singer T, Chernin E, Vardi H, Greenberg D, Israel Ibd Research Nucleus.   +10 more
europepmc   +1 more source

Social functioning violation in patients with paranoid schizophrenia and concomitant somatic and neurologic pathology

, 2017
Valeriy PIDKORYTOV, Natalia Baibarak
openalex   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

RECOGNITION, JUSTICE AND SOCIAL PATHOLOGIES IN AXEL HONNETH'S RECENT WRITINGS [PDF]

, 2007
Stéphane Haber
openalex   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

The social pathology phenomenom implemented in European Unions projects [PDF]

, 2008
Dipomová práce se zabývá sociálně patologicými jevy řešenými v projektech EU, dále vymezením pojmu sociálně patologické jevy,jejich příčin, podmínek vzniku a prevencí těchto jevů.
Smělíková, Jana
core  

Understanding climate injustice as social pathology through the lens of psychoanalysis, recognition theory and critical psychology

, 2022
Christine Bauriedl-Schmidt, Paul Cash, Monika Krimmer, Markus Fellner   +3 more
openalex   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source