Results 51 to 60 of about 661,987 (349)

Self-esteem and peer-perceived social status in early adolescence and prediction of eating pathology in young adulthood [PDF]

open access: yes, 2018
OBJECTIVE: Self-esteem is implied as a factor in the development of eating disorders. In adolescence peers have an increasing influence. Support for the role of self-esteem in eating disorders is ambiguous and little is known about the influence of ...
Deen, Mathijs   +5 more
core   +2 more sources

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Case Report: Uterine Adenosarcoma With Sarcomatous Overgrowth and Malignant Heterologous Elements

open access: yesFrontiers in Medicine, 2022
A 46- year-old woman presented a uterine adenosarcoma originating in the lower uterine segment. The diagnosis was made in an endometrial biopsy and confirmed in the pathological examination of the complete surgical specimen, both identifying heterologous
Yunuén I. García-Mendoza   +9 more
doaj   +1 more source

Urban Pathology [PDF]

open access: yes, 1997
Urban theorists have long debated to what extend and how the social problems of the city have been brought about or exaggerated in some consistent way by the urban environments in which they occur.
Pitcher, Brian L.
core   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Social rank, rank-related life events and eating pathology [PDF]

open access: yes, 2015
This study explored the role of meaning in the link between stress and disordered eating, in particular focusing on social rankPeer ...
Troop, Nicholas
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

[Review of] Judy H. Katz. White Awareness: Handbook for Anti-Racism Training [PDF]

open access: yes, 1980
White Awareness has been created out of a personal and professional struggle and is designed to help whites understand and come to grips with personal, cultural, and institutional racism. The author was the child of refugees from Hitler’s Germany.
Chapin, Helen G.
core   +1 more source

Wildfire Risk as a Socioecological Pathology [PDF]

open access: yes, 2016
Wildfire risk in temperate forests has become a nearly intractable problem that can be characterized as a socioecological “pathology”: that is, a set of complex and problematic interactions among social and ecological systems across multiple spatial and ...
Ager, Alan A.   +22 more
core   +3 more sources

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