Results 61 to 70 of about 293,038 (290)

Wootton B., Social science and social pathology.

, 1960
Davidovitch André. Wootton B., Social science and social pathology.. In: Revue française de sociologie, 1960, 1-2. pp.
Davidovitch, André
core   +1 more source

Palliative care for people with schizophrenia: a qualitative study of an under-serviced group in need

BMC Palliative Care, 2018
Background People with schizophrenia are at risk of receiving poorer end of life care than other patients. They are often undertreated, avoid treatment and are about half as likely to access palliative care. There are limited options for end of life care
Beverley McNamara, Anne Same, Lorna Rosenwax, Brian Kelly   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Eating pathology in relationship to hopelessness [PDF]

, 2001
Plan BPast research evaluating the continuity and discontinuity hypotheses has produced inconclusive results. The continuity hypothesis states that dieting plays a role in the development of bulimia and disordered eating falls on a continuum.
Laffe, Stacia A.
core  

Opinions ofpatients and medical personnel inoutpatient andinpatient health care, as related tothe causes andtreatment ofalcohol-dependence. Opinions ofpatients about alcoholism

Psychiatria i Psychologia Kliniczna, 2011
Introduction: The approach of alcohol-dependent people and medical personnel to alcohol-related problems may affect the efficacy of preventive and therapeutic measures aimed at alcohol-dependence treatment.
Piotr Ścisło, Marcin Kozak, Piotr W. Gorczyca   +2 more
doaj  

The social pathology of polycrisis

Global Sustainability
Non-technical summary The polycrisis, an inadvertent peril of our own making, poses an existential threat to the modern world. Given humanity's innate desire to live safely, and to prosper, what explains this self-inflicted danger?
Stephen J. Purdey
doaj   +1 more source

PROLONGED MASSIVE POLYURIA AFTER RENAL TRANSPLANTATION

Вестник трансплантологии и искусственных органов, 2012
Clinical case of prolonged massive polyuria in patient after renal transplantation is represented in this article. Polyuria lasted for a forty days after kidney transplantation, the larges amount of urine output was 55 litres per day.
A. M. Chernyavskiy, I. V. Karpenko, A. V. Fomichev, A. G. Edemskiy, M. N. Deryagin   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source