Results 41 to 50 of about 160,460 (248)

Prospective healthcare students' perspectives and attitudes on pharmacy as a chosen career path

Exploratory Research in Clinical and Social Pharmacy
Background: With the national increase in the number of colleges and schools of pharmacy as well as the decreased pharmacy school applicant pool in recent years, pharmacy school enrollment challenges are at the forefront of issues facing pharmacy ...
Shadi Doroudgar, Mahsa Sedaghat, Nabeez Noor, Shervin Gorji   +3 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Could Nanotechnology Help to End the Fight Against COVID-19? Review of Current Findings, Challenges and Future Perspectives

International Journal of Nanomedicine, 2021
Ashagrachew Tewabe Yayehrad,1,2 Ebrahim Abdela Siraj,1,2 Gebremariam Birhanu Wondie,1 Atlaw Abate Alemie,1,3 Manaye Tamrie Derseh,1,4 Abyou Seyfu Ambaye4 1Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Health Sciences ...
Yayehrad AT, Siraj EA, Birhanu GB, Alemie AA, Derseh MT, Ambaye AS   +5 more
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Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Ambivalent perspectives on social robots in pharmacy counselling – A qualitative study of regulatory and sector association representatives' views

Finnish Journal of eHealth and eWelfare
Health technological solutions including social robots offer a means to meet the growing needs of the healthcare sector, also in pharmacies. This study explored the receptiveness of the pharmacy sector regarding the use of social robots in medication ...
Sara Rosenberg, Malin Andtfolk, Susanne Hägglund, Mattias Wingren, Sören Andersson, Linda Estman   +5 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Multidisciplinary Effort and Integrative Preparedness: A Lesson for the Foreseen Multivariate COVID-19 Pandemic Flare-Up

Journal of Multidisciplinary Healthcare, 2021
Ashagrachew Tewabe Yayehrad,1,2 Ebrahim Abdela Siraj,1,2 Dawit Kumilachew Yimenu,3 Abyou Seyfu Ambaye,4 Manaye Tamrie Derseh,1,4 Andargachew Almaw Tamene,5 Tamyalew Getahun Yayeh6 1Department of Pharmaceutics and Social Pharmacy, School of Pharmacy ...
Yayehrad AT, Siraj EA, Yimenu DK, Ambaye AS, Derseh MT, Tamene AA, Yayeh TG   +6 more
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The first modern pharmacy in Banja Luka: The Brammer family, three generations of pharmacists [PDF]

Scripta Medica, 2020
Pharmacy activity in Bosnia and Herzegovina was regulated in 1879 by an Order of the Provincial Government, at the beginning of the Austro-Hungarian occupation.
Marković-Peković Vanda
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