Results 51 to 60 of about 90,536 (296)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

What is the value of social prescribing? [PDF]

, 2016
General practice is in crisis. Across the UK different models of social prescribing have evolved to meet the growth in patient attendance. Although there is growing evidence of their efficacy there is little evidence of their value.
Kimberlee, Richard
core   +1 more source

Social prescribing practices and learning across the North West Coast region: essential elements and key challenges to implementing effective and sustainable social prescribing services

BMC Health Services Research, 2023
Introduction Social prescribing has become an important feature of the UK primary care offer. However, there remains limited evidence on how best to implement and deliver social prescribing programmes to maximise effectiveness and long-term ...
Shaima M. Hassan, Adele Ring, Mark Goodall, Katharine Abba, Mark Gabbay, Nadja van Ginneken   +5 more
doaj   +1 more source

Establishing internationally accepted conceptual and operational definitions of social prescribing through expert consensus: a Delphi study

BMJ Open, 2023
Objective The aim of this study was to establish internationally accepted conceptual and operational definitions of social prescribing.Design A three-round Delphi study was conducted.Setting This study was conducted virtually using an online survey ...
Imaan Bayoumi, Rachelle Ashcroft, Christina Godfrey, Kate Mulligan, Caitlin Muhl   +4 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Social prescribing: a review of community referral schemes [PDF]

, 2015
The review aims to set the scene for the conditions under which social prescribing has arisen and consider the efficacy of different referral options. Its objectives are to provide definitions, models and notable examples of social prescribing schemes ...
Thomson, L., Camic, P., Chatterjee, H.
core  

Challenges and Approaches to Green Social Prescribing During and in the Aftermath of COVID-19: A Qualitative Study [PDF]

, 2022
he last decade has seen a surge of interest and investment in green social prescribing, however, both healthcare and social enterprise has been impacted by the COVID-19 crisis, along with restricted access to public green spaces.
Fixsen, Alison, Barrett, S.
core   +1 more source

Incentivised chronic disease management and the inverse equity hypothesis: findings from a longitudinal analysis of Scottish primary care practice-level data

BMC Medicine, 2017
Background The inverse equity hypothesis asserts that new health policies initially widen inequality, then attenuate inequalities over time. Since 2004, the UK’s pay-for-performance scheme for chronic disease management (CDM) in primary care general ...
Richard Lowrie, Alex McConnachie, Andrea E. Williamson, Evangelos Kontopantelis, Marie Forrest, Norman Lannigan, Stewart W. Mercer, Frances S. Mair   +7 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Mental Health Nurse Prescribing: Challenges in Theory and Practice

, 2009
This article addresses the historical context of mental health nursing and its relationship to nurse prescribing.; examines some of the theoretical and philosophical forces that have molded modern mental health nursing, discussing the tensions between ...
Evans, David
core   +1 more source