Results 51 to 60 of about 84,548 (252)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Do people perceive benefits in the use of social prescribing to address loneliness and/or social isolation? A qualitative meta-synthesis of the literature

BMC Health Services Research, 2022
Social prescribing is a means by which clinical services can link individuals who have psychological, social and/or practical needs with non-clinical services within their local community.
M. Liebmann, A. Pitman, Yung-Chia Hsueh, M. Bertotti, E. Pearce   +4 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Building common understanding: seeking consensus and defining social prescribing across contexts – a collective commentary on a Delphi study

BMC Health Services Research
Social prescribing has become a global phenomenon. A Delphi study was recently conducted with 48 social prescribing experts from 26 countries to establish global agreement on the definition of social prescribing.
Caitlin Muhl, Kate Mulligan, Bogdan Chiva Giurca, Marie J. Polley, Gary Bloch, Dominik Alex Nowak, Charlotte Osborn-Forde, Sonia Hsiung, Kheng Hock Lee, Wolfram J. Herrmann, James Robert Baker, Dame Helen Jayne Stokes-Lampard, Sir Sam Everington, Michael Dixon, Isabelle Wachsmuth, Cristiano Figueiredo, Halfdan Thorsø Skjerning, Daniela Rojatz, Yu-Da Chen, Miriam L. Heijnders, Carolyn Wallace, Michelle Howarth, Daisuke Watanabe, Marcello Bertotti, Anu Helena Jansson, Susanna Althini, Felix Holzinger, Darren Glyn Dooler, Siân Brand, Tim James Anfilogoff, Daisy Fancourt, Michelle L. A. Nelson, Stephanie Tierney, Alison Leitch, Hae-Kweun Nam, Kiffer G. Card, Daniel Hayes, Siân Slade, Marie Anne Essam, Gay Anthia Palmer, Vivian Andrea Welch, David Robinson, Laurie Hilsgen, Niall Taylor, Rasmus Østergaard Nielsen, Dragana Vidovic, Emer Maeve McDaid, Louíse Viecili Hoffmeister, Jill Bonehill, Alan Siegel, Alžběta Bártová, David Acurio-Páez, Juan Manuel Mendive, Kerryn Husk   +53 more
doaj   +1 more source

The Self-Sovereign Patient as a Cornerstone of Healthcare 4.0

Blockchain in Healthcare Today
In Healthcare 4.0, we are witnessing a fundamental shift from provider-centric systems to patient-centric models, where individuals, empowered by technologies such as blockchain, the Internet of Medical Things, and artificial intelligence (AI), assume ...
Tomer Jordi Chaffer, Joe Littlejohn, Arun Nadarasa, Claudia Lamschtein   +3 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

A Qualitative Study of National Perspectives on Advancing Social Prescribing Using Co‐Design in Canada

Health Expectations
Introduction Social prescribing offers a formal pathway of connecting patients in the health system with sources of support within the community to help improve their health and well‐being.
Marianne Saragosa, Kate Mulligan, Sonia Hsiung, Srija Biswas, Kiffer Card, Paul C. Hébert, Vivian Welch, Michelle L. A. Nelson   +7 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source