Results 71 to 80 of about 17,224,878 (304)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Social Problems and the Contextual Compromise: Subjectivity, Objectivity, and Knowledge in Everyday Life [PDF]
, 2019 This article builds on recent sociological debates about the explanatory importance of claims-making contexts and the continuing challenges associated with subjectivism and objectivism in social problems research.
Hier, Sean P.
core +2 more sources
Ukrainian Neurosurgical Journal, 2016 Introduction. International Classification of Functioning, Disability and Health (ICF) was adopted by WHO experts in 2001. Comprehensive ICF goal is to provide a unified standard language and define a framework for describing health indicators
Oleg Tarasenko
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Examining and interpreting cinema's view of romantic marriage based on Esterenberg's theory of love [PDF]
مطالعات زن و خانوادهLove fits into a fluid world in which "romantic possibilities" are rapidly passing by. It seems that cinema, as a means of communication affecting the family, is able to provide the society with models of marital commitment.
Samaneh Sadat Sadidpour, Mansoreh Zarean
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Социологическая наука и социальная практика, 2017 The subject of this article is export of higher education services, which becomes an increasingly important part of social and economic development in various countries across the world.
Oleg L. Verevkin
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Russia, China: Poverty Alleviation (Comparative Analysis)
Управленческое консультирование, 2020 Goal and objectives. The article analyzes the state policy of Russia and China on poverty alleviation, conducted a comparative analysis of the strategy of the two countries in solving the problem, basic areas, social programs, measures, measures of ...
I. S. Orlova, G. M. Tsinchenko
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