Results 41 to 50 of about 3,033,607 (304)

Inserting Migrants into the Global Social Protection Floor [PDF]

open access: yes, 2013
The social protection floor (SPF) is a global initiative led by the International Labour Organization (ILO) to provide social security to vulnerable groups.
Ratel, Marie-Hélène   +2 more
core   +1 more source

Social Protection

open access: yesCommonwealth Secretariat Discussion Paper, 2012
The definition of social protection and what it might encompass is currently a contested space for ‘framing’ the debate and practice. Who is making the decisions about its nature and the responses? Who controls what ‘social protection’ means? This discussion paper situates the current debates, analyses practices, and puts forward the Commonwealth ...
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A review of social protection in Latin America [PDF]

open access: yes, 2009
This paper reviews social protection trends and policy responses in Latin America as part of a global scoping study on social protection commissioned by Ford Foundation (See Appendix One for ToR for this paper).
Barrientos, Armando   +1 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Exploring Intergenerational Educational Mobility in Romania Based on the Intentions of Enrolling in Higher Education Among Upper Secondary Education Students

open access: yesSociologie Românească
While education is one of the most important determinants of social position, it remains largely influenced by parental education. Considering the key role of education in the socioeconomic attainment process, this paper explores patterns of ...
Ana-Maria Zamfir   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Researching the Linkages Between Social Protection and Children's Care in Rwanda: The VUP and its Effects on Child Well-Being, Care, and Family Reunification [PDF]

open access: yes, 2014
This research investigates the links between the Vision 2020 Umurenge Programme (VUP), child well-being, children's care and family reunification. It is part of a wider study on the linkages between social protection and children's care in Rwanda, Ghana ...
Helen Shelmerdine, Keetie Roelen
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Social Security: An Investment in Family Protection [PDF]

open access: yes, 2001
When Social Security was passed into law in 1935, it was not intended to be an investment program to which Americans could contribute. Rather, it was established as a risk pool to which all Americans were mandated to contribute in order to insure the ...
Robert J. Myers
core  

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